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Research Article
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Research ArticleView abstract PDF Full textBackground: The lungs clearance index (LCI) is used to assess the efficiency of ventilation distribution homogeneity among the bronchial tree. Purpose: The purpose of this study was to compare LCI with the standard pulmonary functions tests (PFT) as well as some selected gas exchange measures in three groups; healthy individuals, chronic obstructive pulmonary (COPD) and chronic restrictive pulmonary diseases (CRPD). Methods: LCI was determined from the slope of phase-III of the nitrogen washout curve during single breath (SBN2W). PFT and gas exchange measures were determined using metabolic cart, Vmax29. Results: One Way analysis (ANOVA) showed significant (p<0.05) main effects of group membership (Healthy vs. COPD Vs. RLD) on LCI and PFT forced breathing measures (FEV1, FVC, FEV1/FVC ratio). In addition, there was a significant main effe..... ReadMore
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Case ReportView abstract PDF Full textDown syndrome (DS) is the most common congenital abnormality affecting numerous organs and is associated with an increased incidence of many cutaneous diseases. DS is an extensively researched condition but its associated cutaneous diseases are not well studied. Only a small numbers of case reports on lichenoid diseases associated with DS are reported in literature. So far, we know, there is no report published on classical lichen planus with DS until now. We reported a case of lichen planus in an adult patient of Down syndrome. We treated the patient with systemic acitretin. Patient has been observed for last three years. A good result was observed without any complication or relapse.Down syndrome (DS), also known as trisomy 21, is an autosomal chromosomal disorder caused by the presence of al..... ReadMore
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Case ReportView abstract PDF Full textA 14-year-old female presented with acute onset of cough, fever and chest pain. She had a one-month history of cough treated with broad-spectrum antibiotics and bronchodilators. Several hours prior to admission, she developed fever up to 39.5 oC with chills and chest pain with radiation to her back on deep inspiration. Her past medical and family histories were unremarkable. She was a well-developed adolescent female in no acute distress, 98% oxygen saturation in room air and normal breath sounds on auscultation. Laboratory studies revealed leukocytosis (WBC, 16.6 x 103/μl) with a predominance of neutrophils (80%), elevated C-reactive protein (CRP, 89 mg/L) and erythrocyte sedimentation rate (ESR, 75mm). A chest radiograph revealed left upper lobe atelectasis and infiltrate, and a small effusio..... ReadMore
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Case ReportView abstract PDF Full textSubcutaneous Panniculitis-like T-lymphoma (SPTL) is a rare non-epidermotropic cutaneous T cell lymphoma, which perform 1% of all non-Hodgkin’s lymphomas. The lesions are usually localized in the upper limbs and the trunk. the localization on the cheeks is unusual. The diagnosis of SPTCL depends on the pathologic examination of skin biopsy, but the manifestations of SPTCL are varied and mimic autoimmune disorders. We report a case of a subcutaneous panniculitis-like t-cell lymphoma with an unusual localization in the cheek, mimicking a lupus erythematosus panniculitis, evolving since 2 years in a 40-year-old woman...... ReadMore
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Case ReportView abstract PDF Full textLichen amyloidosis (LA) is the most common form of primary cutaneous amyloidosis. It�s a very pruritic hyperkeratotic and coalescent papules usually localized on the anterior tibiae. The diagnostic is clinical, dermoscopy reveals two major dermoscopic patterns characteristic of LA, namely, �central hub� and �scar-like�...... ReadMore
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Case ReportView abstract PDF Full textSarcoidosis is a granulomatous systemic disease of undetermined origin. Its dermatological manifestations are present in 25% of cases and they are very polymorphic. Nail abnormalities are unusual in sarcoidosis and are often an indication of systemic involvement. Dermoscopy of the nail may be very useful in some isolated cases and can guide us to the right diagnosis. We report a rare case of systemic sarcoidosis presenting as nail dystrophy with painful phalanges and underlying bony cysts, treated successfully by oral corticosteroid with good evolution..... ReadMore
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Review ArticleView abstract PDF Full textOcular manifestations of rosacea are commonly nonspecific and variable. The etiology of the inflammation is not fully known and there is no definite diagnostic test for the disease. We often under diagnose the disease, despite the potential for serious sightthreatening sequelae. When evaluating patients with rosacea, dermatologists and family physicians should obtain a careful history of eye complaints and examine the eyelid margins thoroughly. Patients with moderate-to-severe ocular findings will benefit from evaluation by an ophthalmologist. Controlling symptoms and preventing potential risk of blindness should be the aim of early diagnosis and prompt intervention. The mainstay of treatment is good lid hygiene, topical metronidazole, topical azithromycin eye drops, topical cyclosporine, and oral tetracycline. The aim of this review is t..... ReadMore