Nocuous Skin Manifestations of Spironolactone: Drug Induced Leukocytoclastic Vasculitis

Awad Magbri*, Saad Rashid, Zach Crowe, Shaukat Rashid

Received: May 09, 2018;   Published: May 14, 2018

DOI: 10.32474/ADO.2018.01.000103

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Abstract

The author discusses a case of drug induced vasculitis caused by spironolactone which is very rare complication of the drug. The authors give account on the type of vasculitis caused by drug induced allergy and also the differential diagnoses if the presentation is unusual with only hematuria and kidney injury. The benefits of Spironolactone and the side effects are also illustrated.

Keywords: Vasculitis; Drug rash; Spironolactone; Hyperkalemia; ANCA associated vasculitis; Cryoglobulinemia; Leukocytoclastic vasculitis; Hypocomplementemia

Abbrevations: EGFR: Estimated Glomerular Filtration Rate; MRA: Mineral ocorticoid Receptor Antagonist; AGS: American Geriatric Association; LVEF: Left Ventricular Ejection Fraction; CSVV: Cutaneous Small Vessel Vasculitis; IF: Immuno Fluorescence; ANCA: Anti-Neutrophil Cytoplasmic Antibodies; HSP: Henoch-Schonlein Purpura; ESR: Erythrocyte Sedimentation Rate

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