Evaluation of the Prevalence of Gestational Diabetes Using Fasting Blood Glucose and Glycated Heamoglobin in Yenagoa Metropolis

Gborienemi Simeon George*and Duoboye Stephen Enetim

Received: May 17, 2018;   Published: May 22, 2018

DOI: 10.32474/ADO.2018.01.000104

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Abstract

There is understanding that most pregnant women with gestational diabetes mellitus stands the risk of having adverse obstetric and perinatal outcome. The need for an early detection and effective management of this problem with a view to ensure better maternal and fetal protection was the driving thrust for this study. Through the application of spectrophotometric methods employing enzymatic and non-enzymatic systems, the concentration of fasting blood glucose (FBG) and glycated Haemoglobin (HbA1c) were determined in 2nd and 3rd trimester pregnant women and compared with non-pregnant women. Data were analysed using student’s t-test with the aid of Graph pad Prism (R) software version 6.10 at p<0.05 values considered statistically significant. Result reveals that 11% of pregnant women investigated had gestational diabetes mellitus in Yenagoa metropolis. Our findings elucidate the danger of gestational diabetes mellitus, its prevalence and the need to allow for effective proactive intervention program regarding screening and management and in addition highlight areas requiring further research.

Keywords: Gestation; Diabetes mellitus; Fasting blood glucose; Glycated hemoglobin

Abbrevations: FBG: Fasting Blood Glucose; GDM: Gestational Diabetes Mellitus; RBC: Red Blood Cells; EDTA: Ethylene Diamine Tetrachloro Acetic Acid

Abstract| Introduction| Material and Methods| Result| Discussion| Acknowledgement| References|