Assessment of Genetic Mutations in WFS1 & CISD2 in Wolfram Syndrome Human

Volume 1 - Issue 1

Shahin Asadi*, Mahsa Jamali, Hamideh Mohammadzadeh and Mahya Fattahi

Received: January 25, 2018;   Published: February 15, 2018

DOI: 10.32474/OJNBD.2018.01.000104

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Abstract

In this study we have analyzed 30 people. 10 patients Wolfram syndrome and 20 persons control group. The genes WFS1 and CISD2, analyzed in terms of genetic mutations made. In this study, people who have genetic mutations were targeted, with nervous disorders Wolfram syndrome. In fact, of all people with Wolfram syndrome. 10 patients Wolfram syndrome had a genetic mutation in the genes WFS1 and CISD2 Wolfram syndrome. Any genetic mutations in the target genes control group did not show

Keywords: Genetic study; Wolfram syndrome; Mutations The gene WFS1 and CISD2; RT-PCR

Abstract| eneralizations of Wolfram Syndrome| The Cause of Wolfram’s Syndrome| Materials and Methods| Results| Discussion and Conclusion| References|